发明名称 ANTIGEN BINDING PROTEINS THAT BIND PD-L1
摘要 There is disclosed compositions and methods relating to or derived from anti-PD-L1 antibodies. More specifically, there is disclosed fully human antibodies that bind PD-L1, PD-L1-binding fragments and derivatives of such antibodies, and PD-L1-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having PD-L1 related disorders or conditions, including various inflammatory disorders and various cancers.
申请公布号 EP2854843(A2) 申请公布日期 2015.04.08
申请号 EP20130796457 申请日期 2013.05.31
申请人 SORRENTO THERAPEUTICS, INC. 发明人 ZHOU, HEYUE;GASTWIRT, RANDY;SWANSON, BARBARA, A.;GRAY, JOHN, DIXON;KAUFMANN, GUNNAR, F.
分类号 A61K39/00;A61K39/395;C07K16/28 主分类号 A61K39/00
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