发明名称 |
3,4 DIHYDRO-2H-PYRROLO[1,2-a]PYRAZIN-1-ONE DERIVATIVES |
摘要 |
<p>Compounds which are 4,7-disubstituted derivatives of 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one compounds with the formula or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.</p> |
申请公布号 |
EP2376492(B1) |
申请公布日期 |
2015.04.08 |
申请号 |
EP20090783126 |
申请日期 |
2009.09.17 |
申请人 |
NERVIANO MEDICAL SCIENCES S.R.L. |
发明人 |
MIRIZZI, DANILO;CERVI, GIOVANNI;D'ANELLO, MATTEO;PAPEO, GIANLUCA MARIANO ENRICO;FERGUSON, RON;CASUSCELLI, FRANCESCO |
分类号 |
C07D487/04;A61K31/4985;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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