TRIAZOLOPYRIDYL COMPOUNDS AS ALDOSTERONE SYNTHASE INHIBITORS
摘要
This invention relates to triazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
申请公布号
EP2757883(A4)
申请公布日期
2015.04.08
申请号
EP20120833774
申请日期
2012.09.17
申请人
MERCK SHARP & DOHME CORP.
发明人
BENNETT, D. JONATHAN;CAI, JAIQIQANG;CARSWELL, EMMA;COOKE, ANDREW;HOYT, SCOTT, B.;LONDON, CLARE;MACLEAN, JOHN;RATCLIFFE, PAUL;TAYLOR, JERRY ANDREW;XIONG, YUSHENG;SAMANTA, SWAPAN KUMAR;KULKARNI, BHEEMASHANKAR, A.