发明名称 |
METHOD FOR PRODUCING PANCREATIC HORMONE-PRODUCING CELL, PANCREATIC HORMONE-PRODUCING CELL, AND DIFFERENTIATION/INDUCTION PROMOTER |
摘要 |
<p>The method for producing a pancreatic hormone-producing cell according to the present invention is characterized in that a specific differentiation/induction promoter is added to a culture medium in the process of differentiating/inducing of a pluripotent stem cell or a pancreatic tissue stem/progenitor cell into the pancreatic hormone-producing cell. The differentiation/induction promoter to be used is: a polypeptide which comprises an amino acid sequence encoded by DNA comprising the nucleotide sequence represented by SEQ ID NO: 1 or a variant thereof; or a culture supernatant of a cell into which DNA comprising the nucleotide sequence represented by SEQ ID NO: 1 or DNA capable of hybridizing with DNA comprising a nucleotide sequence complementary to the aforementioned DNA under stringent conditions is integrated as a foreign gene.</p> |
申请公布号 |
EP2857500(A1) |
申请公布日期 |
2015.04.08 |
申请号 |
EP20130793805 |
申请日期 |
2013.05.24 |
申请人 |
SAITAMA MEDICAL UNIVERSITY |
发明人 |
TOYOSHIMA, HIDEO;OKAZAKI, YASUSHI;YOKOO, TOMOTAKA;SUGAHARA, IZUMI |
分类号 |
C12N5/071;C12N15/09 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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地址 |
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