| 摘要 |
<p>The present invention relates to a hard capsule compound formulation; and to a manufacturing method of the hard capsule compound formulation, wherein the hard capsule compound formulation comprises (a) a pellet comprising fenofibric acid or a pharmaceutically acceptable salt thereof and an alkalizer; and (b) a tablet comprising atorvastatin or a pharmaceutically acceptable salt thereof and crospovidone in the weight ratio of 1:2.5 to 1:5.5. According to the present invention, the hard capsule compound formulation exhibits excellent dissolution rate and bioavailability and thus can be practically used for a therapeutic agent for hyperlipidemia and hypercholesteremia.</p> |
