| 主权项 |
1. A compound of formula (IA), or a stereoisomer or pharmaceutically acceptable salt thereof:wherein:
Z is C—R1 or N; Q is a heterocyclic ring which contains at least two nitrogen atoms as a member of the atoms forming the ring wherein the at least two nitrogen atoms independently bind to the —CO-substituted aryl group and the —CO—CO—R group at the carbon atom of the carbonyl, respectively; and Q is selected from the group consisting of monocyclic heterocyclyl, bridged-heterocyclyl, bicyclic heterocyclyl, and spirocyclic heterocyclyl; R is selected from the group consisting of alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, heterocycloalkyl or substituted heterocycloalkyl, aryl or substituted aryl and heteroaryl or substituted heteroaryl, said substituents are selected from the group consisting of halo, lower alkyl, amino, lower alkylamino, lower alkyl alkoxy, haloalkoxy, hydroxy, amido, aminocarbonyl, sulfonamido, cyano, alkynyl, alkoxy, aryloxy, carboxy, and carboxylate; R1 is hydrogen, fluoro or chloro; and R2 is hydrogen. |
