| 发明名称 | Treatment of osteoporosis in peri- and post-menopausal women with hepcidin | ||
| 摘要 | The present invention is directed to a method of treating, preventing, or reducing the risk of bone deterioration or osteoporosis in a peri- or post-menopausal female subject. The method involves selecting a peri- or post-menopausal female subject in need of treating, preventing, or reducing the risk of bone deterioration or osteoporosis and administering hepcidin to the selected subject under conditions effective to treat, prevent, or reduce the risk of bone deterioration or osteoporosis. | ||
| 申请公布号 | US8999935(B2) | 申请公布日期 | 2015.04.07 |
| 申请号 | US201012704187 | 申请日期 | 2010.02.11 |
| 申请人 | New York University | 发明人 | Huang Xi |
| 分类号 | A61K38/16;A61K38/17;A61K38/22;A61P19/08;A61P19/10;C07K14/575;A61K31/711 | 主分类号 | A61K38/16 |
| 代理机构 | LeClairRyan, a Professional Corporation | 代理人 | LeClairRyan, a Professional Corporation |
| 主权项 | 1. A method of treating bone deterioration or osteoporosis in a peri- or post-menopausal female subject, said method comprising: selecting a peri- or post-menopausal female subject having bone deterioration or osteoporosis, and administering a hepcidin polypeptide to the selected subject under conditions effective to treat bone density or osteoporosis wherein the hepcidin polypeptide has the amino acid sequence of SEQ ID NO: 2. | ||
| 地址 | New York NY US | ||