| 发明名称 | Methods for treating juvenile idiopathic arthritis by inhibition of TNFα | ||
| 摘要 | The invention provides methods and compositions for the treatment of juvenile idiopathic arthritis (JIA) where a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to treat JIA. In particular, the invention is directed to methods and compositions relating to a fixed dosing regimen for treating JIA with a TNFα inhibitor. | ||
| 申请公布号 | US8999337(B2) | 申请公布日期 | 2015.04.07 |
| 申请号 | US200812157599 | 申请日期 | 2008.06.10 |
| 申请人 | AbbVie Biotechnology Ltd. | 发明人 | Medich John R.;Paulson Susan K.;Noertersheuser Peter A. |
| 分类号 | A61K39/00;A61K39/395;C07K16/24 | 主分类号 | A61K39/00 |
| 代理机构 | Foley Hoag LLP | 代理人 | Foley Hoag LLP |
| 主权项 | 1. A method for treating juvenile idiopathic arthritis (JIA) in a subject comprising administering an isolated human anti-TNFα antibody, or an antigen-binding portion thereof, to the subject, wherein 20 mg of the anti-TNFα antibody, or antigen-binding portion thereof, is administered to the subject if the subject weighs less than 30 kg, or wherein 40 mg of the anti-TNFα antibody, or antigen-binding portion thereof, is administered to the subject if the subject weighs more than or equal to 30 kg. | ||
| 地址 | Hamilton BM | ||