Method for producing cadaverine

摘要

A method of producing cadaverine is more efficient and at a higher yield than production methods by the conventional fermentation methods. The method includes culturing coryneform bacterium/bacteria having a resistance to a pH of 5.5 or less. Preferably, the coryneform bacterium/bacteria has/have lysine decarboxylase activity and, preferably, the coryneform bacterium/bacteria has/have homoserine auxotrophy and/or a resistance to S-(2-aminoethyl)-L-cysteine.

主权项

1. A method of producing cadaverine comprising culturing Corynebacterium glutamicum that is able to grow at a pH of 5.5 or less, wherein said Corynebacterium glutamicum is obtained by subjecting said Corynebacterium glutamicum to a mutagenesis treatment to introduce a mutation to the Corynebacterium glutamicum chromosome, and screening for strain(s) or a progeny thereof able to grow at a pH of 5.5 or less, which give(s) a higher cadaverine yield than parent strain.