<i>Phaleria macrocarpa </i>extract, extraction process and its use as cholesteryl ester transferase protein (CETP) inhibitor

摘要

An extract and/or herbal fraction and pharmaceutical preparation include extract of Phaleria macrocarpa which for the purpose of this invention, is referred to as DLBS1449. The herbal extract according to the teaching of this invention is effectively applicable to inhibit the expression and activity of Cholesteryl Ester Transferase Protein (CETP), increase HDL cholesterol level, decrease LDL cholesterol level without raising blood pressure therefore it is further applicable in atherosclerosis therapy.

主权项

1. A method of treating dyslipidemia or atherosclerosis in a human in need thereof comprising administering a therapeutically effective amount of an extract of Phaleria macrocarpa to said human to treat the dyslipidemia or atherosclerosis in said human.