发明名称 Regulators of MMP-9 and uses thereof
摘要 A method of regulating an activity of metalloproteinase 9 (MMP-9) is disclosed. The method comprises contacting the MMP-9 with an agent which specifically interacts with an OG domain of the MMP-9. Molecules capable of specifically interacting with the OG domain, methods of identifying same, pharmaceutical compositions comprising same and uses thereof are also disclosed.
申请公布号 US8999332(B2) 申请公布日期 2015.04.07
申请号 US201313916633 申请日期 2013.06.13
申请人 Yeda Research and Development Co. Ltd. 发明人 Sagi Irit;Rosenblum Gabriel
分类号 A61K39/395;C12N9/64;A61K38/00 主分类号 A61K39/395
代理机构 代理人
主权项 1. A humanized antibody comprising an antigen recognition domain which specifically interact with an OG domain of MMP-9.
地址 Rehovot IL