发明名称 |
Regulators of MMP-9 and uses thereof |
摘要 |
A method of regulating an activity of metalloproteinase 9 (MMP-9) is disclosed. The method comprises contacting the MMP-9 with an agent which specifically interacts with an OG domain of the MMP-9. Molecules capable of specifically interacting with the OG domain, methods of identifying same, pharmaceutical compositions comprising same and uses thereof are also disclosed. |
申请公布号 |
US8999332(B2) |
申请公布日期 |
2015.04.07 |
申请号 |
US201313916633 |
申请日期 |
2013.06.13 |
申请人 |
Yeda Research and Development Co. Ltd. |
发明人 |
Sagi Irit;Rosenblum Gabriel |
分类号 |
A61K39/395;C12N9/64;A61K38/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
1. A humanized antibody comprising an antigen recognition domain which specifically interact with an OG domain of MMP-9. |
地址 |
Rehovot IL |