Bone delivery device

摘要

Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects.

主权项

1. A method for delivering one or more biologically active molecules to a subject, comprising:
identifying the one or more biologically active molecules, covering at least a portion of one or more devices with a semipermeable component prior to implantation of the one or more devices in the subject, the one or more devices constructed of organic bone and micromachined to reshape a natural internal cavity thereof and to form a plurality of holes in the one or more devices that access the natural internal cavity, wherein the semi-permeable component comprises a layer of confluent cells covering at least a portion of the plurality of holes of the one or more devices, and implanting in the subject the one or more, wherein the one or more biologically active molecules are included in the one or more devices and the one or more biologically active molecules are at least partially surrounded by the semi-permeable component.