发明名称 |
Transition-metal-free silylation of aromatic compounds |
摘要 |
The present invention describes chemical systems and methods for silylating aromatic organic substrates, said system comprising a mixture of (a) at least one organosilane and (b) at least one strong base, said system being substantially free of a transition-metal compound, and said methods comprising contacting a quantity of the organic substrate with a mixture of (a) at least one organosilane and (b) at least one strong base, under conditions sufficient to silylate the aromatic substrate; wherein said system is substantially free of a transition-metal compound. |
申请公布号 |
US9000167(B2) |
申请公布日期 |
2015.04.07 |
申请号 |
US201314043929 |
申请日期 |
2013.10.02 |
申请人 |
California Institute of Technology |
发明人 |
Grubbs Robert H.;Fedorov Alexey;Toutov Anton;Betz Kerry |
分类号 |
C07F7/08 |
主分类号 |
C07F7/08 |
代理机构 |
Baker & Hostetler LLP |
代理人 |
Baker & Hostetler LLP |
主权项 |
1. A method comprising contacting an organic substrate comprising an aromatic moiety with a mixture of (a) at least one organosilane and (b) at least one strong base, under conditions sufficient to silylate the substrate; wherein said mixture and substrate are substantially free of transition-metal compounds. |
地址 |
Pasadena CA US |