Nucleic acid aptamers against plasmodium lactate dehydrogenase and histidine-rich protein II and uses thereof for malaria diagnosis

摘要

The present invention provides nucleic acid aptamers that bind to Plasmodium proteins lactate dehydrogenase and histidine-rich protein II, and uses thereof for the diagnosis of malaria. Aptamers against histidine-rich protein II may be used to detect the presence of Plasmodium species in general, whereas aptamers against lactate dehydrogenase can be used to specifically detect Plasmodium falciparum.

主权项

1. An aptamer for binding to Plasmodium lactate dehydrogenase, the aptamer comprising a nucleic acid sequence of SEQ ID NO: 2.