SYSTEM AND METHOD FOR DELIVERY OF BIOLOGIC AGENTS

摘要

A delivery system for delivering a therapeutic agent to a patient includes a catheter, a stop feature, a container and a bar. The catheter has a proximal end and a distal end and includes a body defining a lumen that extends to the distal end of the catheter. The stop feature is in proximity to the distal end of the catheter. The container is configured to house the therapeutic agent and is insertable and slidably disposable in the lumen of the catheter. The container is also configured to engage the stop feature of the catheter. The bar is slidably disposable in the lumen of the catheter. Sliding of the bar distally in the lumen forces the therapeutic agent out of the container and out of the lumen when the container is engaged with the stop feature. The stop feature is configured to inhibit the container from exiting the lumen.

主权项

1. A system for delivering a therapeutic agent to a patient, comprising:
a catheter having a proximal end and a distal end and comprising a body defining a lumen extending to the distal end of the catheter; a container insertable and slidably disposable in the lumen of the catheter, the container having a first chamber for housing the therapeutic agent, a second chamber and a rupturable membrane between the first chamber and the second chamber to prevent mixing of the therapeutic agent and the contents of the second chamber during storage of the container; a stop feature in proximity to the distal end of the catheter, wherein the container is configured to engage the stop feature and to inhibit the container from exiting the lumen, a first bar slidably disposable in the lumen, wherein sliding the first bar distally in the lumen causes the membrane between the first and second chamber of the container to rupture and forces the therapeutic agent out of the container and out of the lumen when the container is engaged with the stop feature.