| 主权项 |
1. A compound of the formula (I)in which
the ring Q is 8- or 9-membered heteroaryl, R1 is halogen, cyano, difluoromethyl, trifluoromethyl, (C1-C4)-alkyl, hydroxy, oxo or (C1-C4)-alkoxy, n is a number 0, 1 or 2, R2 is trifluoromethyl, (C1-C6)-alkyl, (C3-C8)-cycloalkyl, phenyl or 5- or 6-membered heteroaryl,
where (C1-C6)-alkyl is substituted by a substituent selected from the group consisting of difluoromethyl and trifluoromethyl,where (C1-C6)-alkyl may be substituted by 1 to 3 fluorine substituents,where (C3-C8)-cycloalkyl may be substituted by 1 or 2 substituents independently of one another selected from the group consisting of fluorine, methyl and methoxy,where phenyl is substituted by 1 to 3 fluorine substituents,where phenyl may be substituted by 1 or 2 substituents independently of one another selected from the group consisting of methyl and methoxy,andwhere 5- and 6-membered heteroaryl may be substituted by 1 or 2 substituents independently of one another selected from the group consisting of fluorine and methyl, R3 is difluoromethyl, trifluoromethyl, (C1-C6)-alkyl, (C3-C7)-cycloalkyl, (C1-C6)-alkylsulphonylamino, (C1-C6)-alkoxycarbonylamino, phenyl or 5- or 6-membered heteroaryl,
where (C1-C6)-alkyl, phenyl and 5- or 6-membered heteroaryl may be substituted by 1 to 3 substituents independently of one another selected from the group consisting of halogen, trifluoromethyl, (C1-C4)-alkyl, (C3-C7)-cycloalkyl, difluoromethoxy, trifluoromethoxy and (C1-C6)-alkoxy, R4 is hydroxy or amino,or an N-oxide, salt, salt of the N-oxide thereof. |
