| 摘要 |
A method and apparatus for diagnosing cancer by using genetic information, the method comprising acquiring first gene expression data of a subject, for whom cancer is to be diagnosed, for a gene marker set including at least one gene marker; and determining a possibility of a presence of the cancer of the subject by using the acquired first gene expression data and pre-stored second gene expression data of a normal person group and a cancer patient group, wherein the gene marker set includes gene markers such as pyrroline-5-carboxylate reductase 1 (PYCR1), phosphoglycerate dehydrogenase (PHGDH), glutaminase 2 (liver, mitochondrial) (GLS2), and glutaminase (GLS) among others. |
| 主权项 |
1. A method of diagnosing cancer by using genetic information, the method comprising:
acquiring first gene expression data of a subject, for whom cancer is to be diagnosed, for a gene marker set including at least one gene marker; and determining a possibility of a presence of the cancer of the subject by using the acquired first gene expression data and pre-stored second gene expression data of a normal person group and a cancer patient group, wherein the gene marker set comprises at least one gene marker selected from the group consisting of pyrroline-5-carboxylate reductase 1 (PYCR1), phosphoglycerate dehydrogenase (PHGDH), glutaminase 2 (liver, mitochondrial) (GLS2), glutaminase (GLS), glutamate dehydrogenase 1 (GLUD1), glutamate-ammonia ligase (GLUL), glutamic-oxaloacetic transaminase 1 and soluble (aspartate aminotransferase 1) (GOT1), glutamic-oxaloacetic transaminase 2 and mitochondrial (aspartate aminotransferase 2) (GOT2), glutamic-pyruvate transaminase (alanine aminotransferase) (GPT), glutamic pyruvate transaminase (alanine aminotransferase 2) (GPT2), phosphoserine aminotransferase 1 (PSAT1), asparagine synthetase (glutamine-hydrolyzing) (ASNS), ornithine aminotransferase (OAT), phosphoserine phosphatase (PSPH), aldehyde dehydrogenase 18 family and member A1 (ALDH18A1), and cysteine conjugate-beta lyase cytoplasmic (CCBL1). |
