发明名称 |
NOVEL TRIAZOLOPYRAZINE DERIVATIVES AND USE THEREOF |
摘要 |
The present invention relates to a novel triazolopyrazine derivative or a pharmaceutically acceptable salt thereof; to a pharmaceutical composition containing the same as an active ingredient for inhibiting c-Met tyrosine kinase activity; and to a pharmaceutical composition for preventing or alleviating a hyper-proliferative disorder. The present invention efficiently inhibits c-Met tyrosine kinase activity, and thus can be useful as a therapeutic agent against various hyper-proliferative disorders associated with excessive cellular proliferation and growth due to abnormal kinase activity, for example, cancer, psoriasis, rheumatoid arthritis, or diabetic retinopathy. |
申请公布号 |
CA2923533(A1) |
申请公布日期 |
2015.04.02 |
申请号 |
CA20132923533 |
申请日期 |
2013.09.30 |
申请人 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;HANDOK INC. |
发明人 |
JUNG, HEE JUNG;HA, JAE DU;CHO, SUNG YUN;KIM, HYOUNG RAE;LEE, KWANG HO;LEE, CHONG OCK;CHOI, SANG UN;PARK, CHI HOON |
分类号 |
C07D487/04;A61K31/4985;A61P3/00;A61P9/00;A61P29/00;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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