PHARMACEUTICAL COMPOSITION COMPRISING SOPHOROLIPID IN COMBINATION WITH AN ANTIBIOTIC

摘要

The invention discloses synergistic pharmaceutical composition comprising an antibiotic and sophorolipid, to effectively combat the problem of antibiotic resistance by increasing the permeability of the antibiotic drugs across the outer membrane of bacteria. The sophorolipid being amphiphilic in nature can span through the structurally alike cell membrane and facilitate the entry of antibiotic drug molecules.

主权项

1. A pharmaceutical composition comprising a sophorolipid, an antibiotic and one or more pharmaceutical excipient or carrier or diluent, to combat the antibiotic resistance in a subject, wherein the sophorolipid increases the permeability of the antibiotic onto the outer membrane of a bacterium.