| 发明名称 |
CELL CULTURING ARTICLE AND METHOD FOR MANUFACTURING THEREOF |
| 摘要 |
The disclosure provides a cell culturing article. The cell culturing article includes a substrate having a surface, a hydrophilic copolymer layer positioned on the surface of the substrate, and a plurality of peptide chains individually conjugated to a surface of the hydrophilic copolymer layer. The hydrophilic copolymer layer is copolymerized by a plurality of polyvinyl alcohol units, a plurality of polyvinyl alcohol derivative units, and a plurality of units containing at least one carboxyl group. A method for manufacturing the cell culturing article, a method for culturing undifferentiated stem cells and a method for regulating stem cell differentiation are also provided herein. |
| 申请公布号 |
US2015093828(A1) |
申请公布日期 |
2015.04.02 |
| 申请号 |
US201414188704 |
申请日期 |
2014.02.25 |
| 申请人 |
National Central University |
发明人 |
HIGUCHI AKON;KAO Ta-Chun |
| 分类号 |
C12N5/074;C12N5/0735;C12N5/071 |
主分类号 |
C12N5/074 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A cell culturing article, comprising:
a substrate having a surface; a hydrophilic copolymer layer positioned on the surface of the substrate, wherein the hydrophilic copolymer layer is copolymerized by a plurality of polyvinyl alcohol units, a plurality of polyvinyl alcohol derivative units and a plurality of units containing at least one carboxyl group; and a plurality of peptide chains individually conjugated on a surface of the hydrophilic copolymer layer. |
| 地址 |
TAOYUAN COUNTY TW |
