发明名称 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DIMINUTION OF BONE TISSUE
摘要 A method for prevention and/or treatment of diminution of bone tissue using a composition comprising a compound selected from Withaferin A (WFA), Withanolide A, and Withanone. The composition showed enhanced WFA bioavailability in rodents against plain WFA, promotes bone marrow cell differentiation, and increases the percent of bone volume to tissue volume (BV/TV%) by 3 folds as compared to free Withaferin A (WFA).
申请公布号 WO2015008301(A4) 申请公布日期 2015.04.02
申请号 WO2014IN00475 申请日期 2014.07.16
申请人 COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH 发明人 TRIVEDI, RITU;MISHRA, PRABHAT RANJAN;SINGH, DIVYA;KHEDGIKAR, VIKRAM;KUSHWAHA, PRIYANKA;ADHIKARY, SULEKHA;CHOUDHARY, DHARMENDRA;GAUTAM, JYOTI;KUMAR, AVINASH;KARVANDE, ANIRUDHA;VERMA, ASHWNI;SHARMA, SHWETA;TRIVEDI, PRABODH K;SANGWAN, NEELAM S;SANGWAN, RAJENDER S
分类号 A61K31/366;A61K9/127;A61K31/336;A61P19/00;A61P19/02;A61P19/10 主分类号 A61K31/366
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