| 发明名称 |
METHOD AND DEVICE FOR THE DETERMINATION OF PLATELET FUNCTION UNDER FLOW CONDITIONS |
| 摘要 |
The invention lies in the area of platelet function diagnostics and relates to a method for the determination of platelet function under flow conditions as well as a device for the implementation of this method. The method is particularly suitable for the determination of the effect of clopidogrel and of other P2Y(12) antagonists with antithrombotic activity as well as the determination of P2Y(1) antagonists with antithrombotic activity. |
| 申请公布号 |
US2015093770(A1) |
申请公布日期 |
2015.04.02 |
| 申请号 |
US201414509907 |
申请日期 |
2014.10.08 |
| 申请人 |
SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH |
发明人 |
Rechner Andreas |
| 分类号 |
G01N33/86 |
主分类号 |
G01N33/86 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for the determination of platelet function in a whole blood sample, the method comprising the following steps:
a) passing the blood through a capillary and then through an opening of a partition member; and b) measuring the time that is required for the formation of a thrombus at the opening of the partition member up to closure of the opening; wherein the partition member comprises i) an activator of purinergic receptors and ii) an activator of intracellular adenylate cyclases. |
| 地址 |
Marburg DE |
