| 发明名称 |
COMPOSITIONS AND METHODS FOR THE DETECTION OF ZINC |
| 摘要 |
The invention relates generally to compositions and methods for the detection of zinc. In particular, compositions and methods are provided to detect changes in cellular zinc concentration and to correlate them to cellular phenomena. |
| 申请公布号 |
US2015094524(A1) |
申请公布日期 |
2015.04.02 |
| 申请号 |
US201414503910 |
申请日期 |
2014.10.01 |
| 申请人 |
Northwestern University |
发明人 |
Woodruff Teresa K.;O'Halloran Thomas V.;Kim Alison M.;Que Emily;Kong Betty;Bernhardt Miranda |
| 分类号 |
G01N33/50;A61B17/435;A61D19/04;G01N21/64 |
主分类号 |
G01N33/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of non-invasively detecting Zn release and/or uptake by a cell or cells comprising:
a) contacting a sample comprising a cell or cells with a Zn-responsive probe; b) detecting the signal emitted by the signaling moiety over time; and c) correlating signal emitted with Zn concentration. |
| 地址 |
Evanston IL US |
