| 发明名称 |
ON-COLUMN VIRAL INACTIVATION METHODS |
| 摘要 |
The present invention is directed to a method of inactivating virus that is present during production of a polypeptide of interest. In particular, the present invention is directed to a method of on-column virus inactivation using a low pH and high salt wash solution that effectively inactivates viruses with minimum recovery loss of the polypeptide. |
| 申请公布号 |
WO2015048330(A2) |
申请公布日期 |
2015.04.02 |
| 申请号 |
WO2014US57524 |
申请日期 |
2014.09.25 |
| 申请人 |
BIOGEN IDEC MA INC. |
发明人 |
BOLTON, GLEN;SELVITELLI, KEITH |
| 分类号 |
C07K1/22 |
主分类号 |
C07K1/22 |
| 代理机构 |
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代理人 |
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