In one aspect, the present invention provides novel derivatives of &Dgr;12-PGJ3 and modular synthetic pathways to obtaining &Dgr;12-PGJ3 and derivatives thereof. In some aspects, the present derivatives of &Dgr;12-PGJ3 are useful as chemotherapeutic agents. The present disclosure also describes compositions of these derivatives as well as methods of use of the derivatives thereof.
申请公布号
WO2015048268(A1)
申请公布日期
2015.04.02
申请号
WO2014US57426
申请日期
2014.09.25
申请人
WILLIAM MARSH RICE UNIVERSITY
发明人
NICOLAOU, KYRIACOS, C.;HERETSCH, PHILIPP;HALE, CHRISTOPHER, R. H.;EL GHZAOUI, ABDELLATIF, EL MARROUNI;PULUKURI, KIRAN, KUMAR;YU, RUOCHENG;GROVE, CHARLES