<p>Nanoparticles that activate complement in the absence of biological molecules are described. The nanoparticles are shown to specifically target antigen presenting cells in specifically in lymph nodes, without the use of a biological molecule for targeting. These particles are useful vehicles for delivering immunotherapeutics. Surface chemistries and chemical formulations for the nanoparticles are described.</p>
申请公布号
AU2009285628(B2)
申请公布日期
2015.04.02
申请号
AU20090285628
申请日期
2009.08.28
申请人
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
发明人
HUBBELL, JEFFREY A.;O'NEIL, CONLIN P.;REDDY, SAI T.;SWARTZ, MELODY A.;VELLUTO, DIANA;VAN DER VLIES, ANDRE;SIMEONI, ELEONORA