发明名称 |
METHODS OF DETECTING CHLAMYDIA AND GONORRHEA AND OF SCREENING FOR INFECTION/INFLAMMATION BASED ON GENOMIC COPY NUMBER |
摘要 |
<p>Compositions and methods for detecting Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are provided. The present invention also provides methods and compositions for screening for infection/inflammation based on genomic copy number. Described herein is a method that entails assaying a sample obtained from the urogenital tract of the mammal for an indicator of genomic copy number, wherein a genomic copy number level that is higher than a control genomic copy number level is indicative of the presence of infection or inflammation of the urogenital tract. Also described in a kit of the invention that includes a primer and/or probe for detecting or sequencing an indicator of genomic copy number, wherein the indicator of genomic copy number comprises a nucleic acid sequence that is expected to be present in the genome of the mammal in one or two copies; and a primer and/or probe for detecting or sequencing a nucleic acid sequence that is indicative of a pathogen that infects the urogenital tract or a miRNA correlated with inflammation.</p> |
申请公布号 |
EP2852686(A1) |
申请公布日期 |
2015.04.01 |
申请号 |
EP20130793093 |
申请日期 |
2013.05.22 |
申请人 |
CEPHEID |
发明人 |
WEIR, ALFHAUS;PERSING, DAVID;HIGUCHI, RUSSELL;WANG, JAMES;VANATTA, REUEL;MURRAY, WILLIAM E. |
分类号 |
C12Q1/68;C12N15/11;G01N33/48 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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