Yeast cell with increased pyruvate pool in cytosol and method of producing pyruvate-based metabolite using the same

摘要

A genetically engineered yeast cell that produces a pyruvate-based metabolite from pyruvate, wherein activity of a mitochondrial pyruvate carrier (MPC) is reduced compared to a parent yeast cell and a method of producing the pyruvate-based metabolite using the yeast cell.