发明名称 ヒトdecorinプロモーターの一部の配列を用いてC/EBPα、C/EBPβ、C/EBPδ若しくはp53依存的に任意の遺伝子を発現させる方法、及びそれらの転写誘導能を抑制又は測定する方法
摘要 <p>Disclosed are a method for causing a gene to be expressed in a C/EBPa-, C/EBPß-, C/EBPd- or p53-dependent manner and a method for inhibiting or determining a transcription induction ability of C/EBPa, C/EBPß, C/EBPd or p53, in each of which a partial sequence of human decorin promoter is used. Also disclosed is DNA for use in the above-mentioned methods. The DNA comprises a nucleotide sequence depicted in SEQ ID NO:1, SEQ ID NO:2 or SEQ ID NO:3, a nucleotide sequence produced by substituting or deleting one or more nucleotides in the nucleotide sequence depicted in SEQ ID NO:1, SEQ ID NO:2 or SEQ ID NO:3, or a nucleotide sequence capable of hybridizing with any one of the above-mentioned nucleotide sequences under stringent conditions, and has a function to regulate the transcription induction ability of C/EBPa, C/EBPß, C/EBPd or p53.</p>
申请公布号 JP5692788(B2) 申请公布日期 2015.04.01
申请号 JP20100545776 申请日期 2010.01.07
申请人 发明人
分类号 C12N15/09;C12Q1/68 主分类号 C12N15/09
代理机构 代理人
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