An amino acid sequence is described. The amino acid may comprise a signal sequence that is SEQ ID NO. 1a (or a variant or homologue or derivative or fragment thereof) that is expressed as a fusion protein that comprises a protein of interest. The signal sequence directs secretion of the protein of interest. The protein of interest may be a heterologous protein. Secretion of the fusion protein aids purification.
申请公布号
EP2279248(B1)
申请公布日期
2015.04.01
申请号
EP20090738475
申请日期
2009.04.30
申请人
DUPONT NUTRITION BIOSCIENCES APS
发明人
DERKX, PATRICK MARIA, FRANCISCUS;MULDER, HARM;NIKOLAEV, IGOR