发明名称 |
SYSTEMS FOR TREATING PULMONARY INFECTIONS |
摘要 |
<p>Provided herein are systems for treating a subject with a pulmonary infection, for example, a nontuberculous mycobacterial pulmonary infection, a Burkholderia pulmonary infection, a pulmonary infection associated with bronchiectasis, or a Pseudomonas pulmonary infection. The system includes a pharmaceutical formulation comprising a liposomal aminoglycoside dispersion, and the lipid component of the liposomes consist essentially of electrically neutral lipids. The system also includes a nebulizer which generates an aerosol of the pharmaceutical formulation at a rate greater than about 0.53 gram per minute. The aerosol is delivered to the subject via inhalation for the treatment of the pulmonary infection.</p> |
申请公布号 |
EP2852391(A1) |
申请公布日期 |
2015.04.01 |
申请号 |
EP20130793204 |
申请日期 |
2013.05.21 |
申请人 |
INSMED INCORPORATED |
发明人 |
PERKINS, WALTER;MALININ, VLADIMIR;LI, XINGONG;MILLER, BRIAN;SEIDEL, DOMINIQUE;HOLZMANN, PHILIPP;SCHULZ, HARALD;HAHN, MICHAEL |
分类号 |
A61K31/7036;A61K9/127;A61K31/7024;A61P11/00 |
主分类号 |
A61K31/7036 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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