Diphenyl sulfide derivative and pharmaceutical product which contains same as active ingredient

摘要

[Problem] To provide a diphenyl sulfide derivative which is useful as a pharmaceutical product that has excellent S1P3 antagonist activity.;[Solution] The inventors have discovered that a diphenyl sulfide derivative represented by general formula (1) (wherein R1 represents an alkoxy group having 1-6 carbon atoms, R2 represents a propyl group or an allyl group, X represents methylene or an oxygen atom, and Z represents a halogen atom) has excellent S1P3 antagonist activity as a result of extensive researches for the production of a compound that has S1P3 antagonist activity.;

主权项

1. A diphenyl sulfide derivative, or a pharmaceutically acceptable salt or hydrate thereof, represented by
an (S)-2-amino-4-{2-chloro-4-(5-ethoxy-2-hydroxyphenylthio)phenyl}-2-propylbutylphosphoric acid monoester.