发明名称 Method for detecting prozone phenomenon, analysis method, device for detecting prozone phenomenon, and analysis device
摘要 Provided is a prozone phenomenon detecting method, by which generation of a prozone phenomenon can be detected even when a conventional specimen analysis tool is used, and examinations using an immunochromatography method and the like can be performed efficiently.
申请公布号 US8993344(B2) 申请公布日期 2015.03.31
申请号 US201013258374 申请日期 2010.07.16
申请人 Arkray, Inc. 发明人 Hasegawa Hironori;Ohshiro Kyouichi;Fukunaga Satoshi
分类号 G01N33/53;G01N33/557;G01N33/558 主分类号 G01N33/53
代理机构 Morgan, Lewis & Bockius LLP 代理人 Morgan, Lewis & Bockius LLP
主权项 1. A method for detecting a prozone phenomenon using a specimen analysis tool containing substances that specifically bind to a target component contained in a sample, the specimen analysis tool comprising: a porous base material; a sample supplying portion; a reagent portion; and at least one detection portion, the sample supplying portion, the reagent portion, and the detection portion being arranged on the porous base material from upstream to downstream in a sample moving direction in this order, wherein the reagent portion contains a labeled substance that specifically binds to the target component, the detection portion contains an immobilized substance that specifically binds to the target component, and the target component is detected by detecting a complex of the target component, the labeled substance, and the immobilized substance through detection of a label of the labeled substance in the detection portion, wherein the prozone phenomenon detecting method comprises a process A in which results of detection of the label are plotted along the sample moving direction, and a position of a peak thus generated is determined at its apex at one time point in the detection portion, and wherein when the apex of the peak appears in the latter half of the total peak area in the sample moving direction, a prozone phenomenon is present.
地址 Kyoto JP