| 发明名称 |
SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS |
| 摘要 |
Object of the present invention are substituted piperidines of the formula 1wherein A, R, R, Rand Rare defined as in the description. Another object of the present invention is to provide antagonists of CCR3, to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof. |
| 申请公布号 |
EA021072(B1) |
申请公布日期 |
2015.03.31 |
| 申请号 |
EA20110001398 |
申请日期 |
2010.04.01 |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
GRUNDL MARC;DOLLINGER HORST;GIOVANNINI RICCARDO;HOENKE CHRISTOPH;HOFFMANN MATTHIAS;KRIEGL JAN;MARTYRES DOMNIC;RAST GEORG;SEITHER PETER |
| 分类号 |
C07D401/04;A61K31/4523;A61K31/454;A61P31/00;A61P35/00;A61P37/00;C07D401/14;C07D413/04;C07D413/14;C07D417/14 |
主分类号 |
C07D401/04 |
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