Nitrobenzothiazole derivatives, preparation thereof and therapeutic applications thereof

摘要

The invention relates to the nitrobenzothiazole derivatives of general formula (I): and to the use thereof for treating tuberculosis.;

主权项

1. A compound corresponding to formula (I):for which, R1 represents:
a (C1-C4)alkyl substituted with: one or more halogen atoms; an aryl substituted with one or more groups chosen, independently of one another, from an OH, (C1-C3)alkoxy, (C3-C6)heterocycloalkyl or (C1-C3)fluoroalkoxy group; a heteroaryl optionally substituted with one or more groups chosen, independently of one another, from a (C1-C4)alkyl group and a halogen atom; an unsubstituted heteroaryl-NH; an unsubstituted (C3-C6)cycloalkyl; a (C3-C6)heterocycloalkyl optionally substituted with one or more groups chosen, independently of one another, from a (C1-C3)alkyl, aryl and aryl (C1-C3)alkyl group; or a (C1-C4)alkyl disubstituted with: an unsubstituted aryl; and an unsubstituted (C3-C6)heterocycloalkyl; in the form of a base or an addition salt with an acid or with a base.