发明名称 |
Chiral intermediates useful for the preparation of hydroxyphosphine ligands |
摘要 |
A compound of formula (I), wherein R1 is hydrogen or a hydroxyl protecting group; and R2 and R3 are same or different and are independently selected from halogen or —O—SO2—X; wherein X is —C1-C4 alkyl; C1-C4 alkyl substituted with one or more halogen; or substituted or unsubstituted phenyl wherein said phenyl substituent is selected from halogen, nitro and C1-C4 alkyl; provided that when R3 is bromine, X is not p-toluoyl; and a process for the preparation thereof. |
申请公布号 |
US8993788(B2) |
申请公布日期 |
2015.03.31 |
申请号 |
US201113882580 |
申请日期 |
2011.11.01 |
申请人 |
UPL Limited |
发明人 |
Shroff Jaidev Rajnikant;Shroff Vikram Rajnikant;Shanker Birja |
分类号 |
C07C31/135;C07F9/50;C07C43/21;C07D309/12;C07F7/08;C07C29/149;C07C29/64;C07C67/08;C07C67/14;C07D309/10;C07D309/30 |
主分类号 |
C07C31/135 |
代理机构 |
Merchant & Gould P.C. |
代理人 |
Merchant & Gould P.C. |
主权项 |
1. A compound of formula II:wherein:
R1 is hydrogen or Z; R2 and R3 are same or different and are independently selected from F, Cl, Br, I; Z is a hydroxyl protecting group selected from tetrahydro-2H-pyran-2-yl; tetrahydro-2H-pyran-2-one-3-yl; tetrahydro-2H-pyran-2-methoxy-6-yl; tetrahydro-2H-pyran-2-ethoxy-6-yl; Si(t-Bu)Me2; and —C(O)Ph. |
地址 |
Mumbai, Maharashtra IN |