1,1,1- trifluoro-2- hydroxy-3- phenylpropane derivatives, process for their manufacture, pharmaceutical compositions comprising the same and uses thereof for the preparation of medicaments

摘要

The present invention relates to compounds of formula I wherein A, n, R1a to R1e and R2 to R5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression.