| 发明名称 | Monoclonal antibodies against NKG2A | ||
| 摘要 | The present invention relates to methods of treating immune disorders, particularly autoimmune or inflammatory disorders, and methods of producing antibodies and other compounds for use in therapeutic strategies for treating such disorders. Generally, the present methods involve the use of antibodies or other compounds that prevent the stimulation of NKG2A receptors on NK cells, leading to the lysis of dendritic cells that contribute to the pathology of the disorders. | ||
| 申请公布号 | US8993319(B2) | 申请公布日期 | 2015.03.31 |
| 申请号 | US200511720553 | 申请日期 | 2005.12.27 |
| 申请人 | Innate Pharma S.A.;University of Genova | 发明人 | Moretta Alessandro;Marcenaro Emanuela;Romagne Francois;Andre Pascale |
| 分类号 | C12N5/00;C12N5/07;C12N5/16;C07K16/28;A61K39/00 | 主分类号 | C12N5/00 |
| 代理机构 | Saliwanchik, Lloyd & Eisenschenk | 代理人 | Saliwanchik, Lloyd & Eisenschenk |
| 主权项 | 1. A hybridoma deposited at the CNCM under accession number I-3549. | ||
| 地址 | Marseilles FR | ||