发明名称 |
METHODS FOR BINDING AN EXOGENOUS MOLECULE TO CELLULAR CHROMATIN |
摘要 |
<p>Disclosed herein are methods for binding an exogenous molecule to a binding site within a region of interest in cellular chromatin and methods for identifying a binding site in cellular chromatin for an exogenous molecule. The methods include identification of one or more accessible regions in cellular chromatin, identification of a target site within the accessible region, introduction of the exogenous molecule into the cell, and testing for the binding of the exogenous molecule to the binding site.</p> |
申请公布号 |
CA2407695(C) |
申请公布日期 |
2015.03.31 |
申请号 |
CA20012407695 |
申请日期 |
2001.04.27 |
申请人 |
SANGAMO BIOSCIENCES, INC. |
发明人 |
RASCHKE, EVA;WOLFFE, ALAN P.;CASE, CASEY C. |
分类号 |
C12N15/12;G01N33/559;C07K14/47;C12N5/10;C12N15/00;C12N15/09;C12N15/10;C12N15/62;C12N15/63;C12N15/66;C12N15/67;C12N15/85;C12Q1/68;G01N33/53;G01N33/68;G06F19/22;G06F19/28 |
主分类号 |
C12N15/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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