Methods for fabricating isolated micro- or nano-structures using soft or imprint lithography

摘要

The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique.

主权项

1. A plurality of monodisperse micro or nano sized particles, comprising:
a pharmaceutically or therapeutically active agent, wherein said agent is present throughout the particle; wherein each particle of the plurality has a substantially uniform three-dimensional engineered shape having parallel lateral surfaces and parallel top and bottom surfaces in cross-section, wherein; the size of each particle of the plurality is less than about 100 micrometers in a broadest dimension.