Imidazopyridine derivatives which inhibit the secretion of gastric acid

摘要

The present invention relates to substituted imidazo [1,2-a]pyridines of formula I where R is —CH2COOH or —COOH, which inhibits exogenously or endogenously stimulated gastric acid secretion and can be used in the prevention and treatment of gastric acid related diseases and gastrointestinal inflammatory diseases.

主权项

1. A method for the treatment of a condition selected from gastric acid related diseases, gastrointestinal inflammatory diseases, symptomatic GERD, erosive esophagitis, peptic ulcer disease, heartburn, regurgitation, acid reflux diseases and nausea, comprising administering, to a subject in need thereof, a therapeutically effective amount of a substituted imidazo[1,2-a]pyridine of formula I or a pharmaceutically acceptable salt thereof: where R is —CH2COOH or —COOH.