发明名称 |
LONG SHELF-LIFE KITS AND METHODS FOR STANDARDIZING, VERIFYING, CALIBRATING OR RECALIBRATING DETECTION OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 |
摘要 |
Long shelf-life kits, value-assigned solutions, and methods for standardizing, verifying, calibrating or recalibrating detection of lipoprotein-associated phospholipase A2 having using them are described herein. In particular, described herein are methods of using solutions of rLp-PLA2 that are stable for an extended period of time to standardize, verify, calibrate or recalibrate assays for Lp-PLA2. |
申请公布号 |
US2015086999(A1) |
申请公布日期 |
2015.03.26 |
申请号 |
US201414279148 |
申请日期 |
2014.05.15 |
申请人 |
SCHAAL Thomas D.;SCHOENBRUNNER Erhard Ralf;Zhuo Shaoqiu |
发明人 |
SCHAAL Thomas D.;SCHOENBRUNNER Erhard Ralf;Zhuo Shaoqiu |
分类号 |
G01N33/573 |
主分类号 |
G01N33/573 |
代理机构 |
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代理人 |
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主权项 |
1. A method of recalibrating a calibration curve for detection of lipoprotein-associated phospholipase A2 (Lp-PLA2) from a biological sample using a value-assigned solution of recombinant Lp-PLA2 having a long shelf life, the method comprising:
detecting a first signal from a value-assigned solution having a first predetermined concentration of a recombinant Lp-PLA2 in a buffer solution, wherein the buffer solution comprises a detergent forming a plurality of micelles that stabilize the recombinant Lp-PLA2; and transforming the calibration curve using the first signal. |
地址 |
San Francisco CA US |