TOFA analogs useful in treating dermatological disorders or conditions

摘要

H:drlntenoyi/NRPortbi/DCC/DAR/5055340..].doc.8/04/2 13 This invention is directed to analogs of 5-(tetradecyloxy)-2-furancarboxylic acid (TOFA) and their use in the treatment of dermatological disorders or conditions characterized by sebaceous gland hyperactivity, such as acne and oily skin, and other dermatological disorders and conditions. This invention is also directed to pharmaceutical compositions comprising analogs of TOFA and a pharmaceutically acceptable excipient for dermatological or oral administration. Formula (1) C 14A 2 f lo / RI