发明名称 METHODS FOR MODIFYING PROGRESSION OF OSTEOARTHRITIS
摘要 Methods for modifying progression of osteoarthritis by local administration of a clostridial derivative, such as a botulinum toxin, to an arthritis-affected site are disclosed herein.
申请公布号 US2015086531(A1) 申请公布日期 2015.03.26
申请号 US201314035622 申请日期 2013.09.24
申请人 Allergan, Inc. 发明人 Jiang Guang-Liang;Turkel Catherine
分类号 A61K38/48 主分类号 A61K38/48
代理机构 代理人
主权项 1. A method for treating osteoarthritis in a patient in need thereof, the method comprising locally administering a therapeutically effective amount of a clostridial derivative to an osteoarthritis-affected site of the patient, thereby treating osteoarthritis in the patient; wherein the administering reduces the levels of at least one cartilage-degrading agent, increasing the levels of at least one cartilage-forming component, or both.
地址 Irvine CA US