发明名称 |
CELL-PENETRATING BACTERIAL E3-UBIQITIN-LIGASES FOR USE IN IMMUNOTHERAPY |
摘要 |
The present invention relates to cell-penetrating effector proteins of type III secretion system (T3SS)-containing bacteria of the genus Salmonella or Shigella and variants, fragments and immunmodulatory domains thereof, for use in immunotherapy. The present invention further relates to cell-penetrating effector proteins of type III secretion system (T3SS)-containing bacteria of the genus Salmonella or Shigella and variants, fragments and immunmodulatory domains thereof, for delivering cargo molecules into eukaryotic cells. |
申请公布号 |
WO2015040215(A1) |
申请公布日期 |
2015.03.26 |
申请号 |
WO2014EP70142 |
申请日期 |
2014.09.22 |
申请人 |
WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER |
发明人 |
LUBOS, MARIE-LUISE;SCHMIDT, ALEXANDER;RUETER, CHRISTIAN |
分类号 |
C07K14/25;C07K14/24;C07K14/255;C07K19/00 |
主分类号 |
C07K14/25 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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