发明名称 |
Stabilised protein solutions |
摘要 |
The invention relates to a method of stabilizing highly concentrated protein solutions during ultrafiltration by addition of sucrose to the highly concentrated protein solution, in particular, but not exclusively to a method of stabilizing highly concentrated antibody solutions during ultrafiltration by addition of sucrose to the highly concentrated antibody solution. |
申请公布号 |
US2015086566(A1) |
申请公布日期 |
2015.03.26 |
申请号 |
US201314396389 |
申请日期 |
2013.03.15 |
申请人 |
Novo Nordisk A/S |
发明人 |
Jensen Ole Elvang |
分类号 |
C07K1/34;C07K16/24 |
主分类号 |
C07K1/34 |
代理机构 |
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代理人 |
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主权项 |
1. A method of ultrafiltration of a highly concentrated protein solution, wherein sucrose is added to the solution when the protein concentration of the solution is between 40 and 60 g/L before further concentration by ultrafiltration. |
地址 |
Bagsvaerd DK |