发明名称 Stabilised protein solutions
摘要 The invention relates to a method of stabilizing highly concentrated protein solutions during ultrafiltration by addition of sucrose to the highly concentrated protein solution, in particular, but not exclusively to a method of stabilizing highly concentrated antibody solutions during ultrafiltration by addition of sucrose to the highly concentrated antibody solution.
申请公布号 US2015086566(A1) 申请公布日期 2015.03.26
申请号 US201314396389 申请日期 2013.03.15
申请人 Novo Nordisk A/S 发明人 Jensen Ole Elvang
分类号 C07K1/34;C07K16/24 主分类号 C07K1/34
代理机构 代理人
主权项 1. A method of ultrafiltration of a highly concentrated protein solution, wherein sucrose is added to the solution when the protein concentration of the solution is between 40 and 60 g/L before further concentration by ultrafiltration.
地址 Bagsvaerd DK