Portable system for simultaneously operating optical far field imaging, tomography and spectroscopy

摘要

A portable optical tomography design for performing elastographic deformation mapping of tissues comprises a coherence light source providing one light beam; a scanning microscope comprising a waveguide having two terminals, a coupler disposed on one terminal, an actuating member connected to the waveguide or the coupler, a first optical reflection member, a beam splitter, and a Fourier-domain spectrometer. The waveguide is actuated by the actuator to traverse a horizontal and vertical motion to prescribe a two-dimensional plane for scanning the tissue sample. Optical fiber is used to connect above elements therebetween. The Fourier-domain spectrometer is coupled with the beam splitter and comprises a second reflection member and an interferogram capturing member. An interferogram produced from the Fourier-domain spectrometer is carried over to a digital signal processor and subsequently an optical coherence tomography image device to generate a three-dimensional image for the scanned tissue.

主权项

1. A portable optical tomography system, comprising:
a coherence light source providing at least one light beam; a scanning microscope, comprising:
a waveguide having at least two terminals;a coupler disposed on at least one terminal; andan actuating member connected to the waveguide or the coupler wherein the actuating member operates to control a horizontal motion and a vertical motion of the waveguide to prescribe a two dimensional plane; a first optical reflection member; a beam splitter, which is coupled with the scanning microscope and the optical reflection member through optical fiber, and receives the light beam and splits the light beam into multiple light beams; and a Fourier-domain spectrometer, which is coupled with the beam splitter, and comprises:
a second reflection member; andan interferogram capturing member, substantially arranged with the single mirror, wherein the second reflection member and the interferogram capturing member are substantially arranged at an angle between 89.5° and 90°.