| 发明名称 |
COMPOSITIONS AND METHODS FOR THE PREVENTION OF MICROBIAL INFECTIONS |
| 摘要 |
This disclosure provides methods and compositions to inhibit or prevent infection of a cell by a bacteria that exports DNABII proteins by administering to a tissue infected with the bacteria an effective amount of an antibody that specifically recognizes and binds the DNABII proteins, thereby inhibiting or preventing infection of the bacteria. Treatment methods, screens and kits are further provided. |
| 申请公布号 |
US2015086542(A1) |
申请公布日期 |
2015.03.26 |
| 申请号 |
US201414493051 |
申请日期 |
2014.09.22 |
| 申请人 |
University of Southern California ;Research Institute at Nationwide Children's Hospital |
发明人 |
Goodman Steven D.;Justice Sheryl S. |
| 分类号 |
C07K16/12;G01N33/566 |
主分类号 |
C07K16/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method to inhibit or prevent infection of a cell by a bacteria that exports a DNABII protein, comprising administering to a tissue infected with the bacteria comprising the cell an effective amount of an antibody that specifically recognizes and binds the DNABII protein, thereby inhibiting or preventing infection of the cell. |
| 地址 |
Los Angeles CA US |
