发明名称 |
SMB PROCESS FOR PRODUCING HIGHLY PURE EPA FROM FISH OIL |
摘要 |
<p>The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture which is a fish oil or which is derived from fish oil, which process comprises the steps of:
(i) purifying the feed mixture in a chromatographic separation step, to obtain a first intermediate product; and
(ii) purifying the first intermediate product obtained in (i) in a simulated or actual moving bed chromatographic separation step, to obtain a second intermediate product; and
(iii) purifying the second intermediate product obtained in (ii) in a chromatographic separation step using a different chromatographic apparatus to that used in the second separation step, to obtain the PUFA product; wherein
an aqueous organic solvent is used as eluent in each separation step;
saturated and/or monounsaturated fatty acids present in the feed mixture are removed in the first separation step;
the PUFA product is separated from different components of the feed mixture in steps (ii) and (iii); and
the PUFA product obtained in the third separation step contains EPA or an EPA derivative in an amount greater than 90 wt%.</p> |
申请公布号 |
EP2613860(B1) |
申请公布日期 |
2015.03.25 |
申请号 |
EP20120735934 |
申请日期 |
2012.07.06 |
申请人 |
BASF PHARMA (CALLANISH) LIMITED |
发明人 |
KELLIHER, ADAM;MORRISON, ANGUS;OROSKAR, ANIL;NAIR REMA, RAKESH VIKRAMAN;AGARWAL, ABHILESH |
分类号 |
B01D15/18;C11B3/10;C11C1/00;C11C1/08 |
主分类号 |
B01D15/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|