| 发明名称 |
CD27L antigen binding proteins |
| 摘要 |
The present invention relates to CD27L antigen binding proteins, such an antibodies, polynucleotides encoding said CD27l antigen binding proteins, antibody drug conjugate compositions, and methods for diagnosing and treating diseases associated with CD27L expression. |
| 申请公布号 |
US8987422(B2) |
申请公布日期 |
2015.03.24 |
| 申请号 |
US201213623836 |
申请日期 |
2012.09.20 |
| 申请人 |
Amgen Inc. |
发明人 |
Delaney John M.;Fanslow, III William Christian;King Chadwick Terence |
| 分类号 |
C07K16/30;C07K16/46;C07K16/28;A61K47/48 |
主分类号 |
C07K16/30 |
| 代理机构 |
|
代理人 |
Bulock Joseph W. |
| 主权项 |
1. A CD27L antigen binding protein having a light chain variable domain comprising an LCDR1 as set forth in SEQ ID NO:71; an LCDR2 sequence as set forth in SEQ ID NO:79; and an LCDR3 sequence as set forth in SEQ ID NO:87; and a heavy chain variable domain comprising an HCDR1 as set forth in SEQ ID NO:25; an HCDR2 sequence as set forth in SEQ ID NO:33; and an HCDR3 sequence as set forth in SEQ ID NO:41. |
| 地址 |
Thousand Oaks CA US |
